Article
Lack of association between angiotensin II type 1 receptor gene polymorphism and hypertension in Japanese.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Feb 2003
Ono Koh, Mannami Toshifumi, Baba Shunroku, Yasui Naomi, Ogihara Toshio, Iwai Naoharu
Abstract excerpt
Angiotensin II type 1 (AT1) receptor mediates the vasoconstriction and growth-promoting effect of angiotensin II in humans. It has been reported that a polymorphism of the AT1 receptor gene (an A/C transversion at position 1166; A1166C) may be associated with essential hypertension (HT). However, several conflicting results have also been reported. Therefore, we conducted an association study between A1166C...
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