Article
G alpha 3 regulates the cAMP signaling system in Dictyostelium.
Molecular biology of the cell - 1 Sept 1997
Brandon M A, Podgorski G J
Abstract excerpt
The Dictyostelium discoideum developmental program is initiated by starvation and its progress depends on G-protein-regulated transmembrane signaling. Disruption of the Dictyostelium G-protein alpha-subunit G alpha 3 (g alpha 3-) blocks development unless the mutant is starved in the presence of artificial cAMP pulses. The function of G alpha 3 was investigated by examining the expression of several components of...
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