Article
Developmental morphology and chemotactic responses are dependent on G alpha subunit specificity in Dictyostelium.
Developmental biology - 1 Dec 2007
Hadwiger Jeffrey A
Abstract excerpt
Dictyostelium discoideum expresses multiple G alpha subunits but only a single G beta and G gamma subunit suggesting that the specific response to an external signal depends largely on G alpha subunit function or G protein-independent signaling from the receptor. To test the contribution of G alpha subunit functional specificity, the chimeric G alpha subunits, G alpha2/4 and G alpha5/4, were created and analyzed...
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