Article
Molecular genetics of signal transduction in Dictyostelium.
Annual review of biochemistry - 1 Jan 1996
Parent C A, Devreotes P N
Abstract excerpt
In conditions of starvation, the free living amoebae of Dictyostelium enter a developmental program: The cells aggregate by chemotaxis to form a multicellular structure that undergoes morphogenesis and cell-type differentiation. These processes are mediated by a family of cell surface cAMP receptors (cARs) that act on a specific heterotrimeric G protein to stimulate actin polymerization, activation of adenylyl...
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