Article
Molecular genetic analysis of two G alpha protein subunits in Dictyostelium.
The Journal of biological chemistry - 15 Jan 1991
Kumagai A, Hadwiger J A, Pupillo M, Firtel R A
Abstract excerpt
In Dictyostelium, chemotaxis to folate during growth and cAMP during aggregation is controlled via cell surface receptors. To study the role of two G alpha proteins (G alpha 1 and G alpha 2) in these responses, we examined the physiological and biochemical effects of null mutations caused by anti...
Topics
- Blotting, Southern
- Blotting, Western
- Chemotaxis
- Cyclic AMP
- Cyclic GMP
- Dictyostelium
- Enzyme Activation
- Folic Acid
- Fungal Proteins
- GTP-Binding Proteins
- Genes, Fungal
- Genetic Vectors
- Guanylate Cyclase
- Mutation
- Signal Transduction