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Article

Regulatory role of the G alpha 1 subunit in controlling cellular morphogenesis in Dictyostelium.

Development (Cambridge, England) - 1 Dec 1994

Dharmawardhane S, Cubitt A B, Clark A M, Firtel R A

Abstract excerpt

To determine the function of the Dictyostelium G alpha 1 subunit during aggregation and multicellular development, we analyzed the phenotypes of g alpha 1 null cells and strains overexpressing either wild-type G alpha 1 or two putative constitutively active mutations of G alpha 1. Strains overexpressing the wild-type or mutant G alpha 1 proteins showed very abnormal culmination with an aberrant stalk...

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PMID: 7821221
DOI: 10.1242/dev.120.12.3549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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