Article
High risk genotypes for celiac disease.
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie - 1 Oct 1994
Clerget-Darpoux F, Bouguerra F, Kastally R, Semana G, Babron M C, Debbabi A, Bennaceur B, Eliaou J F
Abstract excerpt
It is known that celiac disease is strongly associated with an HLA class II component and that most patients carry the dimer DQA1*0501, DQB1*0201. We show in this study that the risk for a carrier of this heterodimer is independent from the number of possible heterodimers, from whether DQA1*0501 and DQB1*0201 are in cis or trans position and from the number of DQA1*0501 (one or two) but strongly depends on the...
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