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Article

Inhibition of thymidine transport in dnaA mutants of Escherichia coli.

The Journal of biological chemistry - 22 Aug 1997

Mizushima T, Yokoyama K, Mima S, Tsuchiya T, Sekimizu K

Abstract excerpt

DnaA protein is the initiator of chromosomal DNA replication in Escherichia coli. We report here our evidence that thymidine transport across cytoplasmic membranes in temperature-sensitive dnaA mutants is greatly decreased at a permissive temperature for growth of the mutants. Complementation analysis with a plasmid containing the wild type dnaA gene and P1 phage-mediated transduction confirmed that mutations in...

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Identifiers

PMID: 9261126
DOI: 10.1074/jbc.272.34.21195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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