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Article

Autoregulation of the Escherichia coli replication initiator protein, DnaA, is indirect.

Molecular microbiology - 1 Mar 1997

Smith R W, McAteer S, Masters M

Abstract excerpt

The expression of dnaA is autoregulated, in that transcription of the gene increases when DnaA is inactivated (and initiation of replication prevented) and decreases when DnaA is supplied in excess. However, the inactivation of DnaA does not necessarily lead to increased DnaA production, as dnaA(Ts; temperature sensitive) strains which are integratively suppressed by derivatives of the plasmid R1 do not show...

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Identifiers

PMID: 9106220
DOI: 10.1046/j.1365-2958.1997.3121675.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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