Article
Involvement of the Escherichia coli folate-binding protein YgfZ in RNA modification and regulation of chromosomal replication initiation.
Molecular microbiology - 1 Jan 2006
Ote Tomotake, Hashimoto Masayuki, Ikeuchi Yoshiho, Su'etsugu Masayuki, Suzuki Tsutomu, Katayama Tsutomu, Kato Jun-ichi
Abstract excerpt
The Escherichia coli hda gene codes for a DnaA-related protein that is essential for the regulatory inactivation of DnaA (RIDA), a system that controls the initiation of chromosomal replication. We have identified the ygfZ gene, which encodes a folate-binding protein, as a suppressor of hda mutations. The ygfZ null mutation suppresses an hda null mutation. The over-initiation and abortive elongation phenotypes...
Topics
- Bacterial Proteins
- Carrier Proteins
- Chromosomes, Bacterial
- DNA Replication
- DNA-Binding Proteins
- Escherichia coli
- Escherichia coli Proteins
- Folate Receptors, GPI-Anchored
- GTP Phosphohydrolases
- Mutation
- RNA, Bacterial
- RNA, Transfer