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Article

Threonine 435 of Escherichia coli DnaA protein confers sequence-specific DNA binding activity.

The Journal of biological chemistry - 12 Sept 1997

Sutton M D, Kaguni J M

Abstract excerpt

The Escherichia coli DnaA protein, as a sequence-specific DNA binding protein, promotes the initiation of chromosomal replication by binding to four asymmetric 9-mer sequences termed DnaA boxes in oriC. Characterization of N-terminal, C-terminal, and internal in-frame deletion mutants identified residues near the C terminus of DnaA protein required for DNA binding. Furthermore, genetic and biochemical...

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Identifiers

PMID: 9287298
DOI: 10.1074/jbc.272.37.23017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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