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Article

Mss4 does not function as an exchange factor for Rab in endoplasmic reticulum to Golgi transport.

Molecular biology of the cell - 1 Jul 1997

Nuoffer C, Wu S K, Dascher C, Balch W E

Abstract excerpt

Mss4 and its yeast homologue, Dss4, have been proposed to function as guanine nucleotide exchange factors (GEFs) for a subset of Rab proteins in the secretory pathway. We have previously shown that Rab1A mutants defective in GTP-binding potently inhibit endoplasmic reticulum to Golgi transport, presumably by sequestering an unknown GEF regulating its function. We now demonstrate that these mutants stably...

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Identifiers

PMID: 9243509
DOI: 10.1091/mbc.8.7.1305
PMCID: PMC276154

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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