Article
Molecular role for the Rab binding platform of guanine nucleotide dissociation inhibitor in endoplasmic reticulum to Golgi transport.
The Journal of biological chemistry - 9 Oct 1998
Wu S K, Luan P, Matteson J, Zeng K, Nishimura N, Balch W E
Abstract excerpt
Guanine nucleotide dissociation inhibitor (GDI) regulates the recycling of Rab GTPases involved in vesicle targeting and fusion. We have analyzed the requirement for conserved amino acid residues in the binding of Rab1A and the function of GDI in transport of cargo between the endoplasmic reticul...
Topics
- Biological Transport
- Cell Line
- Endoplasmic Reticulum
- GTP-Binding Proteins
- Golgi Apparatus
- Guanine Nucleotide Dissociation Inhibitors
- Membrane Proteins
- Models, Molecular
- Mutation
- Protein Binding
- Spectrometry, Fluorescence