Article
Mammalian suppressor of Sec4 modulates the inhibitory effect of Rab15 during early endocytosis.
The Journal of biological chemistry - 6 Sept 2002
Strick David J, Francescutti Dina M, Zhao Yali, Elferink Lisa A
Abstract excerpt
Rab15 is a novel endocytic Rab that counters the stimulatory effect of Rab5-GTP on early endocytic trafficking. Rab15 may interfere with Rab5 function directly by sequestering Rab5 effectors or indirectly through novel sets of effector interactions. To distinguish between these possibilities, we examined the effector binding properties of Rab15. Rab15 does not interact directly with the Rab5 effectors rabex-5 and...
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