Requirement of nucleotide exchange factor for Ypt1 GTPase mediated protein transport.

doi:10.1083/jcb.130.5.1051

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Article

Requirement of nucleotide exchange factor for Ypt1 GTPase mediated protein transport.

The Journal of cell biology - 1 Sept 1995

Jones S, Litt R J, Richardson C J, Segev N

Abstract excerpt

Small GTPases of the rab family are involved in the regulation of vesicular transport. It is believed that cycling between the GTP- and GDP-bound forms, and accessory factors regulating this cycling are crucial for rab function. However, an essential role for rab nucleotide exchange factors has not yet been demonstrated. In this report we show the requirement of nucleotide exchange factor activity for Ypt1 GTPase...

Topics

Alleles
Biological Transport
Cell Extracts
Cytoplasmic Granules
Endoplasmic Reticulum
Eukaryotic Initiation Factor-2
Fungal Proteins
GTP Phosphohydrolases
GTP-Binding Proteins
Golgi Apparatus
Guanine Nucleotide Exchange Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Guanine Nucleotides

Guanosine Triphosphate

Mutation

Protein Binding

Proteins

Ribonucleotides

Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 7657691
DOI: 10.1083/jcb.130.5.1051
PMCID: PMC2120555

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7657691-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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