Article
Requirement of nucleotide exchange factor for Ypt1 GTPase mediated protein transport.
The Journal of cell biology - 1 Sept 1995
Jones S, Litt R J, Richardson C J, Segev N
Abstract excerpt
Small GTPases of the rab family are involved in the regulation of vesicular transport. It is believed that cycling between the GTP- and GDP-bound forms, and accessory factors regulating this cycling are crucial for rab function. However, an essential role for rab nucleotide exchange factors has not yet been demonstrated. In this report we show the requirement of nucleotide exchange factor activity for Ypt1 GTPase...
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