Allelic imbalance at chromosome 1q21 in Wilms tumor.

doi:10.1016/s0165-4608(96)00342-1

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Article

Allelic imbalance at chromosome 1q21 in Wilms tumor.

Cancer genetics and cytogenetics - 1 Aug 1997

Law M H, Algar E, Little M

Abstract excerpt

The Wilms tumor suppressor gene 1, WT1, located on chromosome 11p13 is mutated in only a subset of Wilms tumors. Cytogenetic studies of Wilms tumors show that the most frequent structural anomalies after those affecting chromosome 11p are rearrangements of 1q, suggesting that there is a gene invo...

Topics

Alleles
Chromosome Aberrations
Chromosome Banding
Chromosomes, Human, Pair 1
Genes, Wilms Tumor
Humans
Karyotyping
Kidney Neoplasms
Microsatellite Repeats
Trisomy
Wilms Tumor

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