Article
CCAAT-binding factor NF-Y and RFX are required for in vivo assembly of a nucleoprotein complex that spans 250 base pairs: the invariant chain promoter as a model.
Molecular and cellular biology - 1 Aug 1997
Linhoff M W, Wright K L, Ting J P
Abstract excerpt
The events that lead to promoter accessibility within chromatin are not completely understood. The invariant chain (Ii) promoter was used as a model to determine the contribution of different DNA-binding factors in establishing occupancy of a complex promoter. Gamma interferon induction of the Ii...
Topics
- Antigens, Differentiation, B-Lymphocyte
- Base Sequence
- CCAAT-Enhancer-Binding Proteins
- DNA
- DNA Footprinting
- DNA-Binding Proteins
- Genes, MHC Class II
- Glioblastoma
- Histocompatibility Antigens Class II
- Humans
- Models, Genetic
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic