Article
Dissection of the NF-Y transcriptional activation potential.
Nucleic acids research - 1 Jul 1999
de Silvio A, Imbriano C, Mantovani R
Abstract excerpt
NF-Y is a trimeric CCAAT-binding factor with histone fold subunits (NF-YB/NF-YC) and bipartite activation domains located on NF-YA and NF-YC. We reconstituted the NF-Y activation potential in vivo with GAL4 DBD fusions. In the GAL4-YA configuration, activation requires co-expression of the three subunits; with GAL4-YB and GAL4-YC, transfections of the histone fold partners are sufficient, provided that the Q-rich...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
