Article
Interactions between p300 and multiple NF-Y trimers govern cyclin B2 promoter function.
The Journal of biological chemistry - 28 Feb 2003
Salsi Valentina, Caretti Giuseppina, Wasner Mark, Reinhard Wibke, Haugwitz Ulrike, Engeland Kurt, Mantovani Roberto
Abstract excerpt
The CCAAT box is one of the most common elements in eukaryotic promoters and is activated by NF-Y, a conserved trimeric transcription factor with histone-like subunits. Usually one CCAAT element is present in promoters at positions between -60 and -100, but an emerging class of promoters harbor multiple NF-Y sites. In the triple CCAAT-containing cyclin B2 cell-cycle promoter, all CCAAT boxes, independently from...
Topics
- 3T3 Cells
- Animals
- Base Sequence
- CCAAT-Binding Factor
- Cell Cycle
- Cell Line
- Chromatin
- Cyclin B
- Cyclin B2
- Dimerization
- E1A-Associated p300 Protein