Article
NF-Y and the transcriptional activation of CCAAT promoters.
Critical reviews in biochemistry and molecular biology - 1 Jan 2000
Dolfini Diletta, Gatta Raffaella, Mantovani Roberto
Abstract excerpt
The CCAAT box promoter element and NF-Y, the transcription factor (TF) that binds to it, were among the first cis-elements and trans-acting factors identified; their interplay is required for transcriptional activation of a sizeable number of eukaryotic genes. NF-Y consists of three evolutionarily conserved subunits: a dimer of NF-YB and NF-YC which closely resembles a histone, and the "innovative" NF-YA. In this...
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