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Article

Regulation of the class II-associated invariant chain gene in normal and mutant B lymphocytes.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1990

Doyle C, Ford P J, Ponath P D, Spies T, Strominger J L

Abstract excerpt

The invariant chain protein is intracellularly associated with class II major histocompatibility proteins. In many cases, the expression of these molecules appears to be regulated in a similar manner. Contained within the promoter of the invariant chain gene are sequences (X and I gamma 1) that are similar to the X and Y box elements of class II genes, suggesting that these sequences might be involved in its...

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Identifiers

PMID: 2112745
DOI: 10.1073/pnas.87.12.4590
PMCID: PMC54162

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