Article
Regulation of the class II-associated invariant chain gene in normal and mutant B lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1990
Doyle C, Ford P J, Ponath P D, Spies T, Strominger J L
Abstract excerpt
The invariant chain protein is intracellularly associated with class II major histocompatibility proteins. In many cases, the expression of these molecules appears to be regulated in a similar manner. Contained within the promoter of the invariant chain gene are sequences (X and I gamma 1) that a...
Topics
- Animals
- B-Lymphocytes
- Base Sequence
- Burkitt Lymphoma
- Cell Line
- Chloramphenicol O-Acetyltransferase
- Chromosome Deletion
- DNA, Neoplasm
- Deoxyribonuclease I
- Gene Expression Regulation
- Genes, MHC Class II
- Histocompatibility Antigens Class II
- Humans
- Macromolecular Substances