Article
Constitutive and IL-6-induced nuclear factors that interact with the human C-reactive protein promoter.
The EMBO journal - 1 Feb 1990
Majello B, Arcone R, Toniatti C, Ciliberto G
Abstract excerpt
Transcription of the human C-reactive protein (CRP) gene is induced by interleukin-6 (IL-6) during acute inflammation. Important information for inducible CRP expression is located within the 90 bases preceding the transcriptional start site. We show that the CRP promoter contains two adjacent bi...
Topics
- Animals
- Base Sequence
- C-Reactive Protein
- Carcinoma, Hepatocellular
- Cell Line
- DNA-Binding Proteins
- Genes
- HeLa Cells
- Humans
- Interleukin-6
- Liver Neoplasms
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Oligonucleotide Probes
- Plasmids
- Promoter Regions, Genetic
- Rats