Article
Presence of p53 mutations in primary nasopharyngeal carcinoma (NPC) in non-Asians of Los Angeles, California, a low-risk population for NPC.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 1997
Van Tornout J M, Spruck C H, Shibata A, Schmutte C, Gonzalez-Zulueta M, Nichols P W, Chandrasoma P T, Yu M C, Jones P A
Abstract excerpt
Mutatins of the p53 tumor suppressor gene are rare in nasopharyngeal carcinoma (NPC) patients who reside in high-risk areas, such as Southeastern China. Among this high-risk group, a pre-existing infection with the EBV and consumption of Cantonese salted fish are closely associated with NPC. We i...
Topics
- Adolescent
- Adult
- Aged
- Causality
- DNA Mutational Analysis
- Ethnicity
- Female
- Humans
- Los Angeles
- Male
- Middle Aged
- Mutation
- Nasopharyngeal Neoplasms
- Risk