Article
Presence of p53 mutations in primary nasopharyngeal carcinoma (NPC) in non-Asians of Los Angeles, California, a low-risk population for NPC.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 1997
Van Tornout J M, Spruck C H, Shibata A, Schmutte C, Gonzalez-Zulueta M, Nichols P W, Chandrasoma P T, Yu M C, Jones P A
Abstract excerpt
Mutatins of the p53 tumor suppressor gene are rare in nasopharyngeal carcinoma (NPC) patients who reside in high-risk areas, such as Southeastern China. Among this high-risk group, a pre-existing infection with the EBV and consumption of Cantonese salted fish are closely associated with NPC. We investigated the prevalence of p53 mutations in 28 primary NPC specimens from white (including Hispanic) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.