Tumor suppressor genes on frequently deleted chromosome 3p in nasopharyngeal carcinoma

Abstract excerpt

Nasopharyngeal carcinoma (NPC) is a common head and neck malignancy in Southeast Asia, especially in southern China where it reaches a peak incidence of 20 to 30 cases per 100 000 people [1,2] , but is rare in Europe and North America [3] . Several etiologic factors have been associated with NPC, including early infection with EpsteinBarr virus (EBV), genetic predisposition, chemical carcinogens in some...

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