Article
Absence of p53 alterations in nasopharyngeal carcinoma Spanish patients with Epstein-Barr virus infection.
Virus genes - 1 Dec 2003
Burgos Javier S
Abstract excerpt
The objective of this study was to analyse the relationships between the Epstein-Barr virus (EBV) infection and the molecular abnormalities of the p53 oncoprotein in the nasopharyngeal carcinoma (NPC). Fifty-five NPC paraffin samples from a group of Spanish patients with EBV demonstrated presence by nested-PCR and non-isotopic in situ hybridisation, were analysed for p53 expression using immunohistochemistry. The...
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