Article
Alterations of the p53 gene in nasopharyngeal carcinoma.
Journal of virology - 1 Jun 1992
Effert P, McCoy R, Abdel-Hamid M, Flynn K, Zhang Q, Busson P, Tursz T, Liu E, Raab-Traub N
Abstract excerpt
Nasopharyngeal carcinoma (NPC) is a malignancy which is consistently associated with the Epstein-Barr virus (EBV). The structure of the EBV genome in NPC suggests that NPC is a clonal proliferation of epithelial cells which emerges after EBV infection. The disease develops with high incidence in...
Topics
- Animals
- Base Sequence
- Carcinoma
- Cell Transformation, Neoplastic
- Genes, Tumor Suppressor
- Herpesvirus 4, Human
- Humans
- Mice
- Mice, Nude
- Molecular Sequence Data
- Mutagenesis
- Mutation
- Nasopharyngeal Neoplasms
- Neoplasms, Experimental
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Tumor Virus Infections