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Article

Some properties of the hazard function of the two-mutation clonal expansion model.

Risk analysis : an official publication of the Society for Risk Analysis - 1 Jun 1997

Heidenreich W F, Luebeck E G, Moolgavkar S H

Abstract excerpt

We discuss the hazard function of the two-mutation clonal expansion model with time-dependent parameters, with particular emphasis on identifiability of the parameters. We explicitly construct identifiable parameter combinations, and illustrate the properties of the hazard function under perturbations of the underlying biological parameters.

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Identifiers

PMID: 9232020
DOI: 10.1111/j.1539-6924.1997.tb00878.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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