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Article

An improved approximation to the exact solution of the two-stage clonal growth model of cancer.

Risk analysis : an official publication of the Society for Risk Analysis - 1 Aug 1995

Clewell H J, Quinn D W, Andersen M E, Conolly R B

Abstract excerpt

Multistage clonal growth models are of interest for cancer risk assessment because they can explicitly incorporate data on cell replication. Both approximate and exact formulations of the two stage growth model have been described. The exact solution considers the conditional probability of tumor...

Topics

Algorithms
Animals
Carcinogens
Cell Division
Cell Transformation, Neoplastic
Computer Simulation
Incidence
Models, Biological
Mutation
Neoplasms, Experimental
Prevalence
Probability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Risk Assessment

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Identifiers

PMID: 7480946
DOI: 10.1111/j.1539-6924.1995.tb00339.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7480946-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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