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Article

Preventing clonal evolutionary processes in cancer: Insights from mathematical models.

Proceedings of the National Academy of Sciences of the United States of America - 21 Jul 2015

Rodriguez-Brenes Ignacio A, Wodarz Dominik

Abstract excerpt

Clonal evolutionary processes can drive pathogenesis in human diseases, with cancer being a prominent example. To prevent or treat cancer, mechanisms that can potentially interfere with clonal evolutionary processes need to be understood better. Mathematical modeling is an important research tool that plays an ever-increasing role in cancer research. This paper discusses how mathematical models can be useful to...

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Identifiers

PMID: 26195751
DOI: 10.1073/pnas.1501730112
PMCID: PMC4517241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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