Exact solutions of the clonal expansion model and their application to the incidence of solid tumors of atomic bomb survivors.

Abstract excerpt

We derive explicit hazard functions for the clonal expansion model in the "exact formulation" and in the "epidemiological approximation" for the spontaneous rate and for short-time exposure. We investigate which combination of the biological parameters can be determined from the incidence function, and which cannot. We then analyze the incidence data of all solid tumors of atomic bomb survivors (1958-1987). We...

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