Article
On the parameters of the clonal expansion model.
Radiation and environmental biophysics - 1 May 1996
Heidenreich W F
Abstract excerpt
The exact hazard function of the clonal expansion model was analyzed, and it was shown that only three of its four parameters can be determined by fitting to the age dependence of spontaneous tumor incidence rates. The same holds for the survival function.
Topics
- Age Distribution
- Cell Survival
- Cell Transformation, Neoplastic
- Clone Cells
- Humans
- Incidence
- Mutation
- Neoplasms
- Probability
- Proportional Hazards Models
- Stochastic Processes
- Survival Rate