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Article

The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites.

Development (Cambridge, England) - 1 Jul 1997

Soriano P

Abstract excerpt

Platelet-derived growth factors (PDGFs) have been implicated in the control of cell proliferation, survival and migration. Patch mutant mice harbor a deletion including the PDGF alpha receptor gene and exhibit defects of neural crest origin which affect pigmentation in heterozygotes and cranial bones in homozygotes. To verify the role of the PDGF alphaR gene during development, mice carrying a targeted null...

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Identifiers

PMID: 9226440
DOI: 10.1242/dev.124.14.2691

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites.PMID 9226440Read ↗

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