Article
Developmental expression of the alpha receptor for platelet-derived growth factor, which is deleted in the embryonic lethal Patch mutation.
Development (Cambridge, England) - 1 May 1992
Orr-Urtreger A, Bedford M T, Do M S, Eisenbach L, Lonai P
Abstract excerpt
The alpha receptor of PDGF (Pdgfra) is expressed in primitive endoderm and mesoderm derivatives throughout embryogenesis. In the early primitive streak stage the gene is transcribed in the visceral and parietal endoderm. Later it is expressed in the presomitic mesoderm, yolk sac and amnion. During somitogenesis its transcription localizes to the heart and the somites. Subsequently, it is transcribed in the...
Topics
- Animals
- Blotting, Southern
- Chromosome Deletion
- Embryo, Mammalian
- Gene Expression
- Mice
- Mice, Inbred Strains
- Molecular Probe Techniques
- Morphogenesis
- Mutation
- Phenotype