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Article

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

Genes & development - 1 Nov 2016

Fantauzzo Katherine A, Soriano Philippe

Abstract excerpt

Craniofacial development is a complex morphogenetic process, disruptions in which result in highly prevalent human birth defects. While platelet-derived growth factor (PDGF) receptor α (PDGFRα) has well-documented functions in this process, the role of PDGFRβ in murine craniofacial development is not well established. We demonstrate that PDGFRα and PDGFRβ are coexpressed in the craniofacial mesenchyme of...

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Identifiers

PMID: 27856617
DOI: 10.1101/gad.288746.116
PMCID: PMC5131783

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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