Article
Radiation-induced translocations in mice: persistence, chromosome specificity, and influence of genetic background.
Radiation research - 1 Sept 2000
Giver C R, Moore D H, Pallavicini M G
Abstract excerpt
The translocation frequency response in the chromosomes of peripheral blood lymphocytes is widely used for radiation biomonitoring and dose estimation. However, this assay is based upon several assumptions that have not been rigorously tested. It is typically assumed that the translocation frequency in blood lymphocytes reflects the level of genomic damage in other hemopoietic tissues and is independent of the...
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