Article
The Drosophila G-protein-coupled receptor kinase homologue Gprk2 is required for egg morphogenesis.
Development (Cambridge, England) - 1 Jul 1997
Schneider L E, Spradling A C
Abstract excerpt
G protein signaling is a widely utilized form of extracellular communication that is mediated by a family of serpentine receptors containing seven transmembrane domains. In sensory neurons, cardiac muscle and other tissues, G protein-coupled receptors are desensitized through phosphorylation by a family of kinases, the G protein-coupled receptor kinases (GRKs). Desensitization allows a cell to decrease its...
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