Article
Gprk2 controls cAMP levels in Drosophila development.
Developmental biology - 1 May 2001
Lannutti B J, Schneider L E
Abstract excerpt
G protein-coupled receptors mediate their biological responses through the generation of second messengers, such as cAMP. The down-regulation of their activity (desensitization) is carried out, in part, by the family of G protein-coupled receptor kinases, which phosphorylate activated receptors. The Gprk2 gene in Drosophila melanogaster is a putative member of this family. The GPRK2 protein is expressed most...
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