Gprk2 controls cAMP levels in Drosophila development.

doi:10.1006/dbio.2001.0219

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Article

Gprk2 controls cAMP levels in Drosophila development.

Developmental biology - 1 May 2001

Lannutti B J, Schneider L E

Abstract excerpt

G protein-coupled receptors mediate their biological responses through the generation of second messengers, such as cAMP. The down-regulation of their activity (desensitization) is carried out, in part, by the family of G protein-coupled receptor kinases, which phosphorylate activated receptors. The Gprk2 gene in Drosophila melanogaster is a putative member of this family. The GPRK2 protein is expressed most...

Topics

3',5'-Cyclic-AMP Phosphodiesterases
Animals
Cyclic AMP
Cyclic AMP-Dependent Protein Kinases
Cytoskeleton
Drosophila
Drosophila Proteins
Female
G-Protein-Coupled Receptor Kinase 2
Genes, Insect
Genes, Lethal
Infertility
Mutation
Oogenesis
Ovary
Protein Serine-Threonine Kinases
Receptors, Cell Surface
Second Messenger Systems

Source

Open in PubMed

Identifiers

PMID: 11319866
DOI: 10.1006/dbio.2001.0219

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