Article
Transcriptomics and Phenotypic Analysis of gpr56 Knockout in Zebrafish.
International journal of molecular sciences - 23 Apr 2023
Sun Luning, Yang Boyu, Peng Zheng, Yang Tianle, Qin Bin, Ao Jieyu, Yang Yanqun, Wang Jingling, Zheng Lan, Xie Huaping
Abstract excerpt
The adhesion G-protein-coupled receptor is a seven-transmembrane receptor protein with a complex structure. Impaired GPR56 has been found to cause developmental damage to the human brain, resulting in intellectual disability and motor dysfunction. To date, studies on gpr56 deficiency in zebrafish have been limited to the nervous system, and there have been no reports of its systemic effects on juvenile fish at...
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