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Article

Kinase activity-independent regulation of cyclin pathway by GRK2 is essential for zebrafish early development.

Proceedings of the National Academy of Sciences of the United States of America - 23 Jun 2009

Jiang Xi, Yang Peng, Ma Lan

Abstract excerpt

G protein-coupled receptor (GPCR) kinases (GRKs) are known as a family of serine/threonine kinases that function as key regulators of GPCRs, as well as other types of receptors. Extensive studies of GRKs at the cellular and organismal levels have led to a consensus that GRK-catalyzed phosphorylat...

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Identifiers

PMID: 19502428
DOI: 10.1073/pnas.0812105106
PMCID: PMC2700943

Genes

GRK2
PTCH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19502428-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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