Comparison of an activated partial thromboplastin time with a Russell viper venom time test in screening for factor V(Leiden) (FVR506Q).

Article

Comparison of an activated partial thromboplastin time with a Russell viper venom time test in screening for factor V(Leiden) (FVR506Q).

American journal of clinical pathology - 1 Jul 1997

Sweeney J D, Blair A J, King T C

Abstract excerpt

Factor V(Leiden) is the most common abnormality detected in patients examined because of hereditary thrombophilia. The most widely used clot-based screening test is based on the activated partial thromboplastin (aPTT) time. This test has a low sensitivity. A comparison of the aPTT-based test with...

Topics

Factor V
Genetic Testing
Humans
Mutation
Partial Thromboplastin Time
Polymerase Chain Reaction
Predictive Value of Tests
Prothrombin Time
Sensitivity and Specificity
Thrombosis

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