Article
An improved algorithm for activated protein C resistance and factor V Leiden screening.
American journal of clinical pathology - 1 Sept 2013
Herskovits Adrianna Z, Morgan Elizabeth A, Lemire Susan J, Lindeman Neal I, Dorfman David M
Abstract excerpt
OBJECTIVES: To evaluate the performance of a Russell viper venom-based activated protein C resistance (APCR) screening test relative to DNA analysis for the factor V Leiden mutation. METHODS: We evaluated the concordance between Pefakit APCR screening results and DNA analysis for 435 patients homozygous (n = 11), heterozygous (n = 310), or wild-type (n =114) for the G1691A allele. RESULTS: Using receiver...
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