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Article

Improved distinction of factor V wild-type and factor V Leiden using a novel prothrombin-based activated protein C resistance assay.

American journal of clinical pathology - 1 Dec 2004

Wilmer Marianne, Stocker Christoph, Bühler Bea, Conell Brigitte, Calatzis Andreas

Abstract excerpt

A new prothrombin-based activated protein C resistance (APC-R) test is described. In this method, the patient sample is prediluted in a plasma depleted of factor V (FV). A reagent containing APC and a specific activator of FV is added. After an incubation period, clotting is initiated by the addi...

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Source

Identifiers

PMID: 15539375
DOI: 10.1309/T8AV-VH7Q-WGL0-QTF5

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15539375-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Improved distinction of factor V wild-type and factor V Leiden using a novel prothrombin-based activated protein C resistance assay.PMID 15539375Read ↗

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