Article
Assessment of activated protein C resistance using a new and rapid venom-based test: STA Staclot APC-R.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jun 1998
Oger E, Leroyer C, Mercier B, Van Dreden P, Bressollette L, De Saint-Martin L, Le Moigne E, Blouch M T, Thuillier N, Amiral J, Ferec C, Abgrall J F, Mottier D
Abstract excerpt
Activated protein C (APC) resistance is related to a single point mutation in the factor V gene (FV:Q506) and appears to be the most common inherited risk factor for venous thromboembolism. A reliable screening test is therefore useful. We aimed to evaluate a new APC resistance test, on the basis...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Blood Coagulation Tests
- Crotalid Venoms
- Drug Resistance
- Enzyme Activation
- Factor V
- Female
- Humans
- Male
- Middle Aged
- Point Mutation