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Article

Assessment of activated protein C resistance using a new and rapid venom-based test: STA Staclot APC-R.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jun 1998

Oger E, Leroyer C, Mercier B, Van Dreden P, Bressollette L, De Saint-Martin L, Le Moigne E, Blouch M T, Thuillier N, Amiral J, Ferec C, Abgrall J F, Mottier D

Abstract excerpt

Activated protein C (APC) resistance is related to a single point mutation in the factor V gene (FV:Q506) and appears to be the most common inherited risk factor for venous thromboembolism. A reliable screening test is therefore useful. We aimed to evaluate a new APC resistance test, on the basis of the procoagulant activity present in one snake venom of a crotalidae family: STA Staclot APC-R. We studied 36...

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Identifiers

PMID: 9690807
DOI: 10.1097/00001721-199806000-00008

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Assessment of activated protein C resistance using a new and rapid venom-based test: STA Staclot APC-R.PMID 9690807Read ↗

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Activated protein C resistance: the most common risk factor for venous thromboembolism.Semantic proximity Read ↗

Screening for the FV:Q506 mutation--evaluation of thirteen plasma-based methods for their diagnostic efficacy in comparison with DNA analysis.Semantic proximity Read ↗

Activated protein C resistance due to a common factor V gene mutation is a major risk factor for venous thrombosis.Semantic proximity Read ↗

Resistance to activated protein C caused by the factor VR506Q mutation is a common risk factor for venous thrombosis.Semantic proximity Read ↗

Modification of the ProC Global assay using dilution of patient plasma in factor V-depleted plasma as a screening assay for factor V Leiden mutation.Semantic proximity Read ↗

Prevalence of activated protein C resistance and analysis of clinical profile in thromboembolic patients. A Belgian prospective study.Semantic proximity Read ↗

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Proposal for objective evaluation of the performance of various functional APC-resistance tests in genotyped patients.Semantic proximity Read ↗

Inherited resistance to activated protein C caused by presence of the FV:Q506 allele as a basis of venous thrombosis.Semantic proximity Read ↗

Clinical evaluation of a new functional test for detection of activated protein C resistance (Pefakit APC-R Factor V Leiden) at two centers in Europe and the USA.Semantic proximity Read ↗

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