Article
HLA-DRA promoter polymorphism and diversity generation within the immune system.
Human genetics - 1 Jun 1997
Schwiebert L M, Hughes A, Monos D S, Ono S J
Abstract excerpt
Multiple major histocompatibility complex (MHC) alleles exist at most class I and II loci. Polymorphism of MHC polypeptides may reflect either different levels of selective pressure operating on each molecule or different mutation rates at different loci. To gain further insight into this issue, we sequenced the non-coding promoter region of the HLA-DRA gene from several Epstein-Barr virus-transformed B cell...
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