Article
Qualitative and quantitative analysis of HLA-DRB gene expression.
The Journal of rheumatology - 1 Jan 1997
Vincent R, Louis-Plence P, Gaillard F, Clot J, Eliaou J F
Abstract excerpt
Determination of the molecular mechanisms influencing HLA-DRB gene expression would allow better understanding of the regulation of the immune response in normal as well as in pathological conditions. We started an extensive sequencing analysis of the proximal promoter regions of the DRB genes and observed a nucleotide polymorphism involving the classical regulatory regions of the DRB promoters. These nucleotide...
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