Qualitative and quantitative analysis of HLA-DRB gene expression.

Article

Qualitative and quantitative analysis of HLA-DRB gene expression.

The Journal of rheumatology - 1 Jan 1997

Vincent R, Louis-Plence P, Gaillard F, Clot J, Eliaou J F

Abstract excerpt

Determination of the molecular mechanisms influencing HLA-DRB gene expression would allow better understanding of the regulation of the immune response in normal as well as in pathological conditions. We started an extensive sequencing analysis of the proximal promoter regions of the DRB genes an...

Topics

Alleles
Arthritis, Rheumatoid
B-Lymphocytes
Gene Expression
Genes, MHC Class II
HLA-DR Antigens
Humans
Polymerase Chain Reaction
Promoter Regions, Genetic

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