Article
Functional significance of polymorphism among MHC class II gene promoters.
Tissue antigens - 1 Dec 1996
Guardiola J, Maffei A, Lauster R, Mitchison N A, Accolla R S, Sartoris S
Abstract excerpt
The functional significance of polymorphism among MHC class II promoters in man and mouse is here reviewed, mainly in terms of the hypothesis of differential expression. The hypothesis proposes that differences between antigen-presenting cells in MHC class II expression exert a co-dominant effect...
Topics
- Alleles
- Animals
- Antigen-Presenting Cells
- Cell Differentiation
- Genes, MHC Class II
- Histocompatibility Antigens Class I
- Humans
- Immunity
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Regulatory Sequences, Nucleic Acid
- Signal Transduction
- T-Lymphocyte Subsets