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Article

MHC promoter polymorphism in grey wolves and domestic dogs.

Immunogenetics - 1 May 2005

Berggren Karin T, Seddon Jennifer M

Abstract excerpt

A functional immune system requires a tight control over major histocompatibility complex (MHC) gene transcription, as the abnormal MHC expression patterns of severe immunodeficiency and autoimmune diseases demonstrate. Although the regulation of MHC expression has been well documented in humans and mice, little is known in other species. In this study, we detail the level of polymorphism in wolf and dog MHC gene...

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Source

Identifiers

PMID: 15900498
DOI: 10.1007/s00251-005-0776-4

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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