Article
Structure and evolution of the promoter regions of the DQA genes.
Immunogenetics - 1 Jan 1993
Morzycka-Wroblewska E, Harwood J I, Smith J R, Kagnoff M F
Abstract excerpt
HLA-DQ antigens are unique among the class II antigens in that their alpha chains are highly polymorphic. In the present study, we characterized the general structure of the promoter regions of the DQA genes derived from different DR haplotypes and defined their nucleotide sequence polymorphisms. The promoter of each DQA1 allele contains three sequence motifs which are not present in non-DQA related class II...
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