Article
Description of a polymorphism in the regulatory region of the HLA-DRA gene.
Human immunology - 1 Nov 1991
Pinet V, Eliaou J F, Clot J
Abstract excerpt
It was previously reported that the cell membrane expression of HLA class II molecules is tissue specific and variable among individuals. This variation could be explained at the level of gene regulation. Due to the fact that a coordinate regulation of the HLA-DR genes seems to exist, we focused on the HLA-DRA monomorphic gene. In order to study the polymorphism of the HLA-DRA gene regulatory region, we used...
Topics
- Alleles
- Base Sequence
- DNA
- DNA Restriction Enzymes
- Electrophoresis, Polyacrylamide Gel
- Family
- Gene Expression Regulation
- HLA-DR Antigens
- Histocompatibility Testing
- Humans
- Molecular Sequence Data