Article
Sequence polymorphism in the HLA-B promoter region.
Immunogenetics - 1 Jan 1995
Yao Z, Volgger A, Scholz S, Albert E D
Abstract excerpt
Transcription of major histocompatibility complex class I genes is controlled by the class I regulatory complex in the 5' flanking region. To investigate the molecular basis of this region, we studied the polymorphism of the promoter of the HLA-B locus extending from the ATG transcription initiation signal to -284 base pairs (bp) which includes a number of cis-acting elements: interferon response sequence (IRS),...
Topics
- Alleles
- Base Sequence
- Cell Line
- DNA Primers
- HLA-B Antigens
- Humans
- Molecular Sequence Data
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Sequence Alignment
- Sequence Homology, Nucleic Acid